North Park supports a number of missionaries who are serving in the United States, working with the following organizations:
- Coalition for Christian Outreach
- International Students, Inc.
- Light of Life Rescue Mission
- Women's Choice Network
In addition, North Park contributes to a campus ministry position that works in partnership with the Presbytery of the Alleghenies and the CCO to reach and disciple students at Grove City College and Slippery Rock University.